Hydrochloric Acid → 2-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride

HRID 501239ノート

反応式

HRID 501239 の反応式
[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[CH2:18][CH:17]([NH:22]C(=O)C)[CH2:16]3)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2].[ClH:26]>>[ClH:26].[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[CH2:18][CH:17]([NH2:22])[CH2:16]3)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 57933501N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide

生成物 1

HCID 672312832-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride

実験手順

N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide (96 mg) was heated and stirred for 27 hours in 10 ml 2N hydrochloric acid at 100° C. After completion a clear solution occurred. This was evaporated to dryness and the solid residue was used without further purification.

後処理

  1. customThis was evaporated to dryness
  2. customthe solid residue was used without further purification

出典と根拠

ORDレコード
ord-5075e4d3dbed44eabd6eac14669eea2a
出典データセット
uspto-grants-2010_08
特許番号
US07772257B2

反応ノート

読み込み中…