Acetic Acid → 2-Bromo-5-tert-butyl-1,3-dimethylbenzene

HRID 501870

反応式

HRID 501870 の反応式
C(O)(=O)C.[C:5]([C:9]1[CH:10]=[C:11]([CH3:16])[CH:12]=[C:13]([CH3:15])[CH:14]=1)([CH3:8])([CH3:7])[CH3:6].[Br:17]Br>O>[C:5]([C:9]1[CH:10]=[C:11]([CH3:16])[C:12]([Br:17])=[C:13]([CH3:15])[CH:14]=1)([CH3:8])([CH3:7])[CH3:6]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 73785-Tert-butyl-m-xyleneHCID 24408Bromine

生成物 1

HCID 2203642-Bromo-5-tert-butyl-1,3-dimethylbenzene収率 94.7%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Under an inert atmosphere, 225 g of acetic acid was put into a 500 ml three-necked flask, and 24.3 g of 5-t-butyl-m-xylene was added. Then, after adding 31.2 g of bromine, it was reacted at 15-20° C. for 3 hours. The reaction liquid was added to 500 ml of water, and the deposited precipitate was filtrated. It was washed with 250 ml of water twice and 34.2 g of white solid was obtained.

後処理

  1. customwas reacted at 15-20° C. for 3 hours
  2. customThe reaction liquid
  3. filtrationthe deposited precipitate was filtrated
  4. washIt was washed with 250 ml of water twice

出典と根拠

ORDレコード
ord-bda8c24223b24e88ad61a1e994bf420d
出典データセット
uspto-grants-2010_08
特許番号
US07772360B2

関連ノート

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