Methanol → Hexanoic acid, 2-methyl-, methyl ester
反応式
[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH3:9])[C:3]([OH:5])=[O:4].S(=O)(=O)(O)O.[CH3:15]O>O>[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH3:9])[C:3]([O:5][CH3:15])=[O:4]参加物
5
反応条件
- 温度
- 50 °C
実験手順
A solution of 2-methylhexanoic acid (20 g, 153 mmol) in methanol (500 mL) was treated with concentrated sulfuric acid (8.0 mL) and heated to 50° C. for 16 h. The reaction was diluted with water and extracted with ether. The combined organic layers were dried and concentrated to afford 20.57 g (93%) of methyl 2-methylhexanoate as a colorless liquid.
後処理
- extractionextracted with ether
- customThe combined organic layers were dried
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-dd7c0667478e4394b22e5f59ab7fce31
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07776896B2
反応ノート
読み込み中…