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HRID 5033作成日：2026年10月27日

1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide → 1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane diacetate

https://huagongshe.com/reaction/5033

反応式

関与物質

役割名称HCID仕込み量
反応物1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodideHCID 19088834—
反応物Methanol--water (1/1)HCID 22242641—
生成物1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane diacetateHCID 67867054—

反応手順

30.0 g (0.048 mol) of 1,12-bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide in 300 ml of methanol/water (1:1) were filtered through a column containing 250 g of ion exchanger (OH- form). The free guanidine base obtained after working up was dissolved in methanol and converted into the diacetate with excess glacial acetic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05242948
出典データセットuspto-grants-1993_09
ORD IDord-62caf7e77d574b0eacf847ea9cbf3833
出典メモuspto-grants-1993_09