Hydrochloric Acid → Iminoethyl methoxyacetate hydrochloride

HRID 50377

反応式

HRID 50377 の反応式
[CH3:1][O:2][CH2:3][C:4]#[N:5].C([OH:8])C.[ClH:9].[CH2:10]([O:12][CH2:13]C)C>>[ClH:9].[CH3:10][O:12][CH2:13][C:1]([O:2][CH2:3][CH:4]=[NH:5])=[O:8]

参加物

5

反応物 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 3283Diethyl EtherHCID 74442Methoxyacetonitrile

生成物 1

HCID 57478929Iminoethyl methoxyacetate hydrochloride

実験手順

A solution of 35.5 g (0.50 mol) of methoxyacetonitrile in 29 mL (23 g, 0.50 mol) of ethanol and 30 mL of absolute diethylether was cooled to 0° C. and over 1 hour 22.5 g (0.62 mol) of hydrogen chloride gas was introduced, whilst towards the end of the introduction of gas the reaction product crystallized out. To complete the precipitation 130 mL of diethylether were added and the colorless needles were filtered off. Yield: 66.4 g (86% of theory); melting point: 117° C.-118° C.

後処理

  1. additionwas introduced, whilst towards the end of the introduction of gas the reaction product
  2. customcrystallized out
  3. customthe precipitation 130 mL of diethylether
  4. additionwere added
  5. filtrationthe colorless needles were filtered off

出典と根拠

ORDレコード
ord-e4097f5d8b4a439a99ee79dba119e741
出典データセット
uspto-grants-2004_03
特許番号
US06710055B2

関連ノート

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