M-Xylene → Cyanuric chloride

HRID 50418

反応式

HRID 50418 の反応式
[N:1]1[C:8]([Cl:9])=[N:7][C:5]([Cl:6])=[N:4][C:2]=1[Cl:3].[Cl-].[Al+3].[Cl-].[Cl-].[OH-].[Al+3].[OH-].[OH-].[C:18]1([CH3:25])[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=1>ClC1C=CC=CC=1>[N:1]1[C:8]([Cl:9])=[N:7][C:5]([Cl:6])=[N:4][C:2]=1[Cl:3].[Cl:3][C:2]1[N:4]=[C:5]([C:23]2[CH:22]=[CH:21][C:20]([CH3:24])=[CH:19][C:18]=2[CH3:25])[N:7]=[C:8]([C:23]2[CH:22]=[CH:21][C:20]([CH3:24])=[CH:19][C:18]=2[CH3:25])[N:1]=1.[CH3:25][C:18]1[CH:19]=[C:20]([CH3:24])[CH:21]=[CH:22][C:23]=1[C:2]1[N:4]=[C:5]([C:23]2[CH:22]=[CH:21][C:20]([CH3:24])=[CH:19][C:18]=2[CH3:25])[N:7]=[C:8]([C:23]2[CH:22]=[CH:21][C:20]([CH3:24])=[CH:19][C:18]=2[CH3:25])[N:1]=1

参加物

8

反応物 4

HCID 7929M-XyleneHCID 7954Cyanuric chlorideHCID 6451240Aluminum(III) ChlorideHCID 10176082Aluminum Hydroxide

生成物 3

HCID 7954Cyanuric chloride収率 98%HCID 710591,3,5-Triazine, 2-chloro-4,6-bis(2,4-dimethylphenyl)-HCID 224759882,4,6-Tris(2,4-dimethylphenyl)-1,3,5-triazine

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

To a stirring mixture of 3.7 g (1 eq) of cyanuric chloride, 8 g (3 eq) of aluminum chloride in 50 mL chlorobenzene was added 0.39 g (0.5 eq) of aluminum hydroxide at ice-bath temperature. After 10 min of stirring, 1.9 eq of m-xylene was added. The cooling bath was removed after 10 min and the reaction mixture stirred at room temperature. HPLC analysis after 20 h at room temperature showed 98% of cyanuric chloride conversion to 2-chloro-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and 2,4,6-tris(2,4-dimethylphenyl)-1,3,5-triazine, formed in a ratio of 80:20.

後処理

  1. customThe cooling bath was removed after 10 min
  2. stirringthe reaction mixture stirred at room temperature
  3. waitHPLC analysis after 20 h at room temperature showed

出典と根拠

ORDレコード
ord-a6adafa98b074b1a86687059c1c36a2f
出典データセット
uspto-grants-2004_03
特許番号
US06710177B2

関連ノート

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