化工社化工社 化学情報印刷レポート · 研究参考用
2-Aminopyridine → N-alpha-t-BOC-L-phenylalanine 2-aminopyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Aminopyridine | HCID 10439 | — |
| 反応物 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 反応物 | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| 生成物 | N-alpha-t-BOC-L-phenylalanine 2-aminopyridine | HCID 131722899 | — |
反応手順
The acylated phenylalanine anilide imprint molecule was synthesized in three steps. (1) N-α-t-BOC-L-phenylalanine was coupled with 2-aminopyridine using DCC to give N-α-t-BOC-L-phenylalanine-2-aminopyridine. (2) The α-amine was then deprotected with TFA to give N-α-L-phenylalanine-2-aminopyridine. (3) To create a compound having the properties of a surfactant, the free amine was then acylated with decanoic acid using DCC to give N-α-decyl-L-phenylalanine-2-aminopyridine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06713416B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-e4e5c5db7a4045c7934fd55d1008f962 |
| 出典メモ | uspto-grants-2004_03 |