Methyl 4-Formylbenzoate → Methyl 4-({[2-(5-fluoro-2-methoxyphenyl)ethyl]imino}methyl)benzoate
反応式
[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:11][CH3:12])=[C:6]([CH2:8][CH2:9][NH2:10])[CH:7]=1.[CH:13]([C:15]1[CH:24]=[CH:23][C:18]([C:19]([O:21][CH3:22])=[O:20])=[CH:17][CH:16]=1)=O>C(O)C>[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:11][CH3:12])=[C:6]([CH2:8][CH2:9][N:10]=[CH:13][C:15]2[CH:24]=[CH:23][C:18]([C:19]([O:21][CH3:22])=[O:20])=[CH:17][CH:16]=2)[CH:7]=1参加物
4
実験手順
9.00 g (53 mmol) of 2-(5-fluoro-2-methoxyphenyl)ethylamine and 8.73 g (53 mmol) of methyl 4-formylbenzoate are dissolved in 450 ml of ethanol, the mixture is heated at reflux for 2 hours and the solvents are then evaporated under reduced pressure.
後処理
- temperaturethe mixture is heated
- temperatureat reflux for 2 hours
- customthe solvents are then evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-e524e8956d144e79be95e7b0fb3a58d2
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07781470B2
反応ノート
読み込み中…