1-(2,4-Dichlorophenyl)piperazine → 5-Chloro-3-{4-[4-(2,4-dichlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochloride

HRID 506934

反応式

HRID 506934 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[F:11])[NH:7][C:6](=[O:12])[C:5]2([CH2:15][CH2:16][CH2:17][CH2:18]Cl)[CH2:13][CH3:14].[Cl:20][C:21]1[CH:26]=[C:25]([Cl:27])[CH:24]=[CH:23][C:22]=1[N:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[F:11])[NH:7][C:6](=[O:12])[C:5]2([CH2:15][CH2:16][CH2:17][CH2:18][N:31]1[CH2:30][CH2:29][N:28]([C:22]2[CH:23]=[CH:24][C:25]([Cl:27])=[CH:26][C:21]=2[Cl:20])[CH2:33][CH2:32]1)[CH2:13][CH3:14]

参加物

3

反応物 2

HCID 27375271-(2,4-Dichlorophenyl)piperazineHCID 684638165-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one

生成物 1

HCID 684665185-Chloro-3-{4-[4-(2,4-dichlorophenyl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one monohydrochloride

実験手順

The title compound is prepared according to process H by applying processing method 2 starting from 5-chloro-3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 1-(2,4-dichlorophenyl)-piperazine.

出典と根拠

ORDレコード
ord-8b1f8b3ef1f04116b64d7c12dc0f9c1f
出典データセット
uspto-grants-2010_08
特許番号
US07786129B2

関連ノート

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