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HRID 507413作成日：2026年10月25日

2-Fluorobenzoyl chloride → 2-fluoro-N-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-benzamide

https://huagongshe.com/reaction/507413

反応式

関与物質

役割名称HCID仕込み量
反応物2-Fluorobenzoyl chlorideHCID 9808—
反応物3-[2-(4-Amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-oneHCID 68468184—
生成物2-fluoro-N-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-benzamideHCID 68465194—

反応手順

Synthesis in analogy to Example 8 starting from 3-[2-(4-amino-phenyl)-2-oxo-ethyl]-2-methyl-5,5-diphenyl-3,5-dihydro-imidazol-4-one and 2-fluoro-benzoyl chloride to yield 2-fluoro-N-{4-[2-(2-methyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-yl)-acetyl]-phenyl}-benzamide. LC/MS at 254 nm; [M+H] 506; Rt 3.438 min.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07786155B2
出典データセットuspto-grants-2010_08
ORD IDord-6ce771f6d19c419eaaddf46e7fd2c690
出典メモuspto-grants-2010_08