Hydroxylamine → 4-Phenylcyclohexanone oxime

HRID 510745

反応式

HRID 510745 の反応式
[C:1]1([CH:7]2[CH2:12][CH2:11][C:10](=O)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:14][OH:15].O>C(O)C>[C:1]1([CH:7]2[CH2:12][CH2:11][C:10](=[N:14][OH:15])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 787HydroxylamineHCID 962WaterHCID 786054-Phenylcyclohexanone

生成物 1

HCID 3438824-Phenylcyclohexanone oxime収率 61.38%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To a solution of 4-phenylcyclohexanone (1.50 g, 8.609 mmol) in 95% ethanol (20 ml) was added 50% hydroxylamine in water (5.276 ml, 86.09 mmol), and the reaction was heated to reflux for 1 hour. The reaction was allowed to cool to ambient temperature, and the product was precipitated by the slow addition of water. The solids were collected via filtration to yield 1.0 g of the title compound (61.38% yield).

後処理

  1. temperaturethe reaction was heated
  2. temperatureto reflux for 1 hour
  3. customthe product was precipitated by the slow addition of water
  4. filtrationThe solids were collected via filtration

出典と根拠

ORDレコード
ord-b58103c0762d46d8bfb51620daad589c
出典データセット
uspto-grants-2015_08
特許番号
US09096567B2

関連ノート

読み込み中…