Hydrochloric Acid → 4-(Pentafluorosulfanyl)benzoyl chloride
反応式
[Cl:1][C:2](Cl)(Cl)[C:3]1[CH:8]=[CH:7][C:6]([S:9]([F:14])([F:13])([F:12])([F:11])[F:10])=[CH:5][CH:4]=1.[OH2:17].Cl>>[F:10][S:9]([F:14])([F:13])([F:12])([F:11])[C:6]1[CH:7]=[CH:8][C:3]([C:2]([Cl:1])=[O:17])=[CH:4][CH:5]=1参加物
4
実験手順
Into a 50 mL flask equipped with a stirrer were placed 16.08 g (50 mmol) of 4-trichloromethyl(pentafluorosulfanylbenzene) prepared in Example 1 and 406 mg (5 mol %) of FeCl3. The bath was heated to 70° C. to 75° C., and 900 mg (50 mmol) of water was added dropwise over at least 2 hours. HCl gas was generated during the addition. After the addition was complete, the mixture was heated with stirring for 1 hour. This mixture was distilled under reduced pressure to yield 5.59 g of 4-pentafluorosulfanylbenzoic chloride (product yield: 42%).
後処理
- customInto a 50 mL flask equipped with a stirrer
- temperatureThe bath was heated to 70° C. to 75° C.
- additionAfter the addition
- temperaturethe mixture was heated
- distillationThis mixture was distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-b438193e9b2546e08712a3b4e4677931
- 出典データセット
- uspto-grants-2015_08
- 特許番号
- US09102608B2
反応ノート
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