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3,4-Dichlorophenyl isocyanate → 4-(3,4-Dichlorophenylcarbamoyl)oxyimino-5-methyl-5-phenyl-3-phenylaminothiazolidine-2-thione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-Dichlorophenyl isocyanate | HCID 7607 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-Hydroxyimino-5-methyl-5-phenyl-3-phenylamino-thiazolidine-2-thione | HCID 86588495 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-(3,4-Dichlorophenylcarbamoyl)oxyimino-5-methyl-5-phenyl-3-phenylaminothiazolidine-2-thione | HCID 86588496 | — |
反応手順
A mixture of 4-hydroxyimino-5-methyl-5-phenyl-3-phenylamino-thiazolidine-2-thione (0.19 g), triethylamine (0.06 g) and 3,4-dichlorophenylisocyanate in tetrahydrofuran (3 ml) was stirred for 2 days at room temperature. The solvent was evaporated under reduced pressure and the residue was purified by column chromatography (chloroform) to yield 4-(3,4-Dichlorophenylcarbamoyl)oxyimino-5-methyl-5-phenyl-3-phenylaminothiazolidine-2-thione (0.13 g) having a melting point of 95-96° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06713629B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-a3460076cd15444cb33a9bccf66d5f5a |
| 出典メモ | uspto-grants-2004_03 |