化工社化工社 化学情報印刷レポート · 研究参考用
tert-butyl N-(4-chlorophenyl)carbamate → (2-Amino-5-chloro-phenyl)-(2,4-difluoro-phenyl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-butyl N-(4-chlorophenyl)carbamate | HCID 546372 | — |
| 反応物 | 2,4-Difluorobenzoyl chloride | HCID 588081 | — |
| 生成物 | (2-Amino-5-chloro-phenyl)-(2,4-difluoro-phenyl)-methanone | HCID 64423774 | 20% |
反応手順
In a manner similar to that described above for compound 1aa, 4-Chloro-N-Boc-aniline and 2,4-difluoro-benzoyl chloride were converted to 1w (20% yield) MS m/z=268 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09102678B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-58cdec6ff740401b8563bb9cd855a2ab |
| 出典メモ | uspto-grants-2015_08 |