化工社化工社 化学情報印刷レポート · 研究参考用
tert-butyl N-(4-chlorophenyl)carbamate → (2-Amino-5-chloro-phenyl)-(2-chloro-6-fluoro-phenyl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-butyl N-(4-chlorophenyl)carbamate | HCID 546372 | — |
| 反応物 | 2-Chloro-6-fluorobenzoyl chloride | HCID 2736547 | — |
| 生成物 | (2-Amino-5-chloro-phenyl)-(2-chloro-6-fluoro-phenyl)-methanone | HCID 67505353 | 42% |
反応手順
In a manner similar to that described above for compound 1aa, 4-Chloro-N-Boc-aniline and 2-chloro-6-fluoro-benzoyl chloride were converted to 1ab (42% yield) MS m/z=284 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09102678B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-d25e6dcecf4342d29476108ff3b63072 |
| 出典メモ | uspto-grants-2015_08 |