化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl mercaptan → 2-(Benzylthio)-3-nitropyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl mercaptan | HCID 7509 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(Benzylthio)-3-nitropyridine | HCID 507300 | 96% |
反応手順
In a similar fashion using route 38 general procedure 92, 2-chloro-3-nitro-pyridine(2 g, 12.7 mmol), Na2CO3 (1.75 g, 16.6 mmol), benzylmercaptan (1.87 g, 15.1 mmol) and EtOH (20 ml) at 90° C. for 4 h gave the title compound (3 g, 96%) which was used in the next step without further purification. The structure was confirmed by 1H NMR.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09102688B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-29ad9f09c69c4c328a084f911264c85c |
| 出典メモ | uspto-grants-2015_08 |