化工社化工社 化学情報印刷レポート · 研究参考用
4-Chloro-8-nitroquinazoline → HCID 11462514、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Chloro-8-nitroquinazoline | HCID 11458471 | — |
| 反応物 | p-Toluene sulphonyl hydrazine hydrate | HCID 86669768 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 11462514 | HCID 11462514 | 95% |
反応手順
p-Toluene sulphonyl hydrazine hydrate (390 mg, 2.1 mmol) was added to a solution of 4-chloro-8-nitro-quinazoline 477 (400 mg, 1.91 mmol) in DCM at (10 ml) and the mixture was stirred at room temperature for 24 h. The mixture was concentrated in vacuo and washed with Et20 to give the title compound (650 mg, 95%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09102688B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-df26422ddfb343fabb844c4eb5bb9369 |
| 出典メモ | uspto-grants-2015_08 |