Hydrochloric Acid → 2-Hydrazinylpyridine-4-carbonitrile hydrochloride salt

HRID 514338

反応式

HRID 514338 の反応式
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[ClH:11]>CCOC(C)=O>[ClH:11].[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 201187142-Hydrazinylpyridine-4-carbonitrile

生成物 1

HCID 867254842-Hydrazinylpyridine-4-carbonitrile hydrochloride salt収率 95%

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

To a solution of 2-hydrazinylpyridine-4-carbonitrile (2.13 g, 16 mmol, PREPARATION 2) in EtOAc (10 mL) was added HCl (4 M in EtOAc, 15 mL) at rt. It was then stirred at rt for 30 min. The reaction mixture was filtered and washed with EtOAc and dried to give the title compound (3.13 g, 95%) as a yellow solid.

後処理

  1. filtrationThe reaction mixture was filtered
  2. washwashed with EtOAc
  3. customdried

出典と根拠

ORDレコード
ord-a78809a1a8e44a92b3a4ade8149e844e
出典データセット
uspto-grants-2015_08
特許番号
US09107916B2

関連ノート

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