化工社化工社 化学情報印刷レポート · 研究参考用
1-Phenyl-2-propanol → Phenylacetone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Phenyl-2-propanol | HCID 94185 | — |
| 反応物 | HCID 178418287 | HCID 178418287 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Phenylacetone | HCID 7678 | 85.7% |
反応手順
A solution of 1-phenylpropan-2-ol (2.72 g, 20 mmol) in CH2Cl2 (20 mL) was added pyridinium chlorochromate (PCC, 5.4 g, 25 mmol) at 0° C. and the mixture was stirred for 3 h. The mixture was concentrated and purified by flash column chromatography (PE/EtOAc=20:1) to give the title compound (2.3 g, 84%) as a yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09107916B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-1d69b9b3861e4ae3bdfff58d082611de |
| 出典メモ | uspto-grants-2015_08 |