Triethyl phosphite → 2,7-Dimethoxy-9H-carbazole
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=2)=[C:5]([N+:17]([O-])=O)[CH:4]=1.P(OCC)(OCC)OCC>CCOCC>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]2[C:9]3[C:14](=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=3)[NH:17][C:5]=2[CH:4]=1参加物
4
反応条件
- 温度
- 90 °C
実験手順
Compound 39 (8.47 g) was divided into eight portions (1.06 g each). Then, P(OEt)3 (per 7 mL) was added to each portion. The resulting mixtures were subjected to argon blow, heated to 90° C., kept at this temperature for 3 days, cooled, and diluted with ether. The precipitate obtained was filtered and washed with CH2Cl2. Yield of carbazole 40: 3.33 g.
後処理
- temperaturecooled
- customThe precipitate obtained
- filtrationwas filtered
- washwashed with CH2Cl2
出典と根拠
- ORDレコード
- ord-c472b7f49cd24bbda5ed6e494f78fa6a
- 出典データセット
- uspto-grants-2015_08
- 特許番号
- US09108916B2
反応ノート
読み込み中…