化工社化工社 化学情報印刷レポート · 研究参考用
Boron trifluoride → 3-Allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Boron trifluoride | HCID 6356 | — |
| 反応物 | Allyl Alcohol | HCID 7858 | — |
| 反応物 | 7-Aminocephalosporanic acid | HCID 441328 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | 3-Allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid | HCID 131716787 | — |
反応手順
Using the procedure of Step A of Example 8, 27.2 g of 7-amino-cephalosporanic acid, 170 ml of the etherate of boron trifluoride, 136 ml of allyl alcohol and 115 ml of triethylamine were reacted and the 9 g of raw product was purified successively twice with hot hydrochloric acid and ammonium hydroxide to obtain 4.72 g of 3-allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05243043 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-dcaa90fa626041689c210e2969f0e25b |
| 出典メモ | uspto-grants-1993_09 |