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4-Bromo-2-methyl-1-phenoxybenzene → 2-Methyl-4-(4,4,5,5-tetrametyl-1,3,2-dioxaborolan-2-yl)phenyl phenyl ether
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-2-methyl-1-phenoxybenzene | HCID 22736253 | — |
| 反応物 | 2-Phenoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)benzonitrile | HCID 22736340 | — |
| 溶媒 | Ethylacetate heptane | HCID 21899848 | — |
| 生成物 | 2-Methyl-4-(4,4,5,5-tetrametyl-1,3,2-dioxaborolan-2-yl)phenyl phenyl ether | HCID 66915583 | — |
反応手順
The title compound was prepared in a 77% from 4-bromo-2-methyl-1-phenoxybenzene in a similar manner to that described for the preparation 2-phenoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)benzonitrile: 1H NMR (DMSO-d6, 400 MHz) δ 7.67(s, 1H), 7.50(d, 1H), 7.38(t, 2H), 7.14(t, 1H), 6.94(d, 2H), 6.80(d, 1H), 2.21(t, 3H); TLC (heptane/ethyl acetate 9:1) Rf0.6.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06713474B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-693f2654c9d3446ba4e01380a9ba9440 |
| 出典メモ | uspto-grants-2004_03 |