2-Bromobenzaldehyde → 2-[4-(Ethoxycarbonyl)-1-methyl-1H-pyrrol-2-yl]benzoic acid

HRID 515866

反応式

HRID 515866 の反応式
C[C:2]1[NH:3][CH:4]=[CH:5][C:6]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8].N1[CH:16]=[CH:15][C:14]([C:17]([O:19]CC)=[O:18])=[CH:13]1.Br[C:23]1C=C(Cl)C=C[C:24]=1C=O.Br[C:33]1C=CC=CC=1C=O>>[CH2:10]([O:9][C:7]([C:6]1[CH:5]=[C:4]([C:15]2[CH:16]=[CH:24][CH:23]=[CH:13][C:14]=2[C:17]([OH:19])=[O:18])[N:3]([CH3:33])[CH:2]=1)=[O:8])[CH3:11]

参加物

5

実験手順

The procedure is in accordance with the process of Preparation 1, replacing, on the one hand, the ethyl 2-methyl-1H-pyrrole-3-carboxylate used in Step A by ethyl 1H-pyrrole-3-carboxylate and, on the other hand, the 2-bromo-4-chlorobenzaldehyde used in Step B by 2-bromo-benzaldehyde.

後処理

  1. customThe procedure is in accordance with the process of Preparation 1

出典と根拠

ORDレコード
ord-b90d3a29f88d48c3ad693f959fb3b10e
出典データセット
uspto-grants-2015_08
特許番号
US09108983B2

関連ノート

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