Ethyl 2-methyl-3-pyrrolecarboxylate → HCID 117833689、化合物

反応式

[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][C:6]=1[C:7]([O:9][CH2:10]C)=[O:8].[CH3:12][C:13]1N[CH:15]=[CH:16][C:17]=1[C:18]([O:20]C)=[O:19].Br[C:23]1C=C(Cl)C=CC=1C=O.BrC1C=[C:39]([O:41][CH3:42])C=CC=1C=O>>[CH3:39][O:41][C:42]1[CH:12]=[CH:13][C:17]([C:18]([OH:20])=[O:19])=[C:16]([C:4]2[N:3]([CH3:23])[C:2]([CH3:1])=[C:6]([C:7]([O:9][CH3:10])=[O:8])[CH:5]=2)[CH:15]=1

参加物

反応物 4

HCID 136747Ethyl 2-methyl-3-pyrrolecarboxylate

HCID 111276412-Bromo-4-methoxybenzaldehyde

HCID 12333388Methyl 2-methyl-1H-pyrrole-3-carboxylate

HCID 131547102-Bromo-4-chlorobenzaldehyde

生成物 1

HCID 117833689HCID 117833689、化合物

実験手順

The procedure is in accordance with the process of Preparation 1, replacing the ethyl 2-methyl-1H-pyrrole-3-carboxylate used in Step A by methyl 2-methyl-1H-pyrrole-3-carboxylate and also the 2-bromo-4-chlorobenzaldehyde used in Step B by 2-bromo-4-methoxybenzaldehyde.