Hydrochloric Acid → 4-(10-Allyloxydecyloxy)benzoic acid

HRID 5163

反応式

HRID 5163 の反応式
[CH2:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]I)[CH:2]=[CH2:3].C[O:17][C:18]([C:20]1[CH:21]=[CH:22][C:23]([OH:26])=[CH:24][CH:25]=1)=[O:19].C(=O)([O-])[O-].[K+].[K+].[OH-].[K+].Cl>C(O)C>[CH2:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][O:26][C:23]1[CH:24]=[CH:25][C:20]([C:18]([OH:19])=[O:17])=[CH:21][CH:22]=1)[CH:2]=[CH2:3]

参加物

7

反応物 5

HCID 313Hydrochloric AcidHCID 7456MethylparabenHCID 11430Potassium CarbonateHCID 14797Potassium HydroxideHCID 1979791310-Iododecyl allyl ether

生成物 1

HCID 197979084-(10-Allyloxydecyloxy)benzoic acid収率 80%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
80 °C

実験手順

70 mmol (22.7 g) of 10-iododecyl allyl ether, 70 mmol (10.6 g) of methyl p-hydroxybenzoate, and 70 mmol (9.6 g) of potassium carbonate were refluxed in absolute ethanol for 15 hours. After addition of an aqueous potassium hydroxide solution (containing 4.0 g of potassium hydroxide) into the reaction solution, the resulting mixture was further heated at 80° C. for 5 hours. After conclusion of the reaction, the reaction solution was acidified with hydrochloric acid, and the acidified reaction solution was then concentrated under reduced pressure. Water was added to the residue to form a suspension, and the insoluble matter was collected and was then dried, to obtain 18.7 g of 4-(10-allyloxydecyloxy)benzoic acid (Yield: 80%).

後処理

  1. customAfter conclusion of the reaction
  2. customthe acidified reaction solution
  3. concentrationwas then concentrated under reduced pressure
  4. additionWater was added to the residue
  5. customto form a suspension
  6. customthe insoluble matter was collected
  7. customwas then dried

出典と根拠

ORDレコード
ord-259cdfd8194a46da8519bc2b1b2c0ec8
出典データセット
uspto-grants-1993_09
特許番号
US05243065

関連ノート

読み込み中…