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Potassium Carbonate → 5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate | HCID 2776019 | — |
| 反応物 | Methyl 5-hydroxypyridine-2-carboxylate | HCID 4715126 | — |
| 生成物 | 5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester | HCID 57475878 | — |
反応手順
In a manner analogous to that described in example 24 a), the alkylation of the 5-hydroxy-pyridine-2-carboxylic acid methyl ester with potassium carbonate and trifluoro-methanesulphonic acid 2,2,3,3,3-pentafluoropropyl ester yielded the 5-(2,2,3,3,3-pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester as a light yellow oil. MS (ISP): m/z=285 [M]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09115098B2 |
| 出典データセット | uspto-grants-2015_08 |
| ORD ID | ord-40b10e743e474a6b9505fdf91121d675 |
| 出典メモ | uspto-grants-2015_08 |