8-Bromo-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one → US10023592, Example 234

反応式

[F:1][C:2]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH2:14][CH3:15])(=[O:13])=[O:12])=[CH:7][C:6]=1B1OC(C)(C)C(C)(C)O1.C(S(C1C=CC(OCCC)=C(B2OC(C)(C)C(C)(C)O2)C=1)(=O)=O)C.Br[C:55]1[C:60]2[N:61]=[CH:62][N:63]=[CH:64][C:59]=2[C:58](=[O:65])[N:57]([CH3:66])[CH:56]=1.BrC1C2N=C(C3C=NN(C)C=3)N=CC=2C(=O)N(C)C=1>>[F:1][C:2]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH2:14][CH3:15])(=[O:12])=[O:13])=[CH:7][C:6]=1[C:55]1[C:60]2[N:61]=[CH:62][N:63]=[CH:64][C:59]=2[C:58](=[O:65])[N:57]([CH3:66])[CH:56]=1