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Glycerol → Apomorphine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glycerol | HCID 753 | — |
| 反応物 | 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)- | HCID 9410 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Apomorphine | HCID 6005 | — |
反応手順
The particulate apomorphine is combined with sodium carboxymethylcellulose and glycerol. The resulting mixture is mixed thoroughly (i.e., using a vacuum mixer) and homogenized. Water is added to the mixture (with extensive mixing) to form a hydrogel containing suspended nanoparticles of apomorphine hydrochloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09326981B2 |
| 出典データセット | uspto-grants-2016_05 |
| ORD ID | ord-93ad2b7e24c4493792906455e992d7bf |
| 出典メモ | uspto-grants-2016_05 |