1-(2,3-Xylyl)piperazine → 3-(2-(4-(2,3-dimethylphenyl) piperazine-1-yl)ethyl)-2-ethylquinazoline-4(3H)-one

HRID 520288ノート

反応式

HRID 520288 の反応式
[CH2:1]([C:3]1[N:12]([CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][N:18]([C:21]3[CH:26]=[CH:25][CH:24]=[C:23]([C:27](F)(F)F)[CH:22]=3)[CH2:17][CH2:16]2)[C:11](=[O:31])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1)[CH3:2].[CH3:32]C1C(C)=CC=CC=1N1CCNCC1>>[CH3:32][C:22]1[C:23]([CH3:27])=[CH:24][CH:25]=[CH:26][C:21]=1[N:18]1[CH2:19][CH2:20][N:15]([CH2:14][CH2:13][N:12]2[C:11](=[O:31])[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[N:4]=[C:3]2[CH2:1][CH3:2])[CH2:16][CH2:17]1

参加物

3

反応物 2

HCID 705411-(2,3-Xylyl)piperazineHCID 668251862-ethyl-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-one

生成物 1

HCID 569441123-(2-(4-(2,3-dimethylphenyl) piperazine-1-yl)ethyl)-2-ethylquinazoline-4(3H)-one

実験手順

This compound was prepared in compliance with the procedure described in 7d, using 1-(2,3-dimethylphenyl)piperazine instead of 1-(3-(trifluoromethyl)phenyl)piperazine.

後処理

  1. customThis compound was prepared in compliance with the procedure

出典と根拠

ORDレコード
ord-2bfd1006985647daa4aa3d332ae162c0
出典データセット
uspto-grants-2016_05
特許番号
US09326984B2

反応ノート

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