Formamide → 6-Nitro-3,4-dihydroquinazolin-4-one

HRID 52034

反応式

HRID 52034 の反応式
[N+:1]([C:4]1[CH:12]=[C:8]([C:9]([OH:11])=O)[C:7]([NH2:13])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH:14]([NH2:16])=O>>[N+:1]([C:4]1[CH:12]=[C:8]2[C:7](=[CH:6][CH:5]=1)[N:13]=[CH:14][NH:16][C:9]2=[O:11])([O-:3])=[O:2]

参加物

3

反応物 2

HCID 713FormamideHCID 120322-Amino-5-nitrobenzoic acid

生成物 1

HCID 1353985026-Nitro-3,4-dihydroquinazolin-4-one収率 82%

実験手順

Using an analogous procedure to that described in the first paragraph of the portion of Example 1 which is concerned with the preparation of starting materials, 5-nitroanthranilic acid was reacted with formamide to give 6-nitroquinazolin-4-one in 82% yield, m.p. 268°-271° C.

出典と根拠

ORDレコード
ord-66692aa56892493bab2bcf912181f8a8
出典データセット
uspto-grants-1997_04
特許番号
US05616582

関連ノート

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