化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 1,4-Dimethyl-1H-pyrazole-3-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 1,4-Dimethyl-1H-pyrazole-3-carboxylic acid | HCID 5325685 | — |
| 生成物 | 1,4-Dimethyl-1H-pyrazole-3-carbonyl chloride | HCID 58356380 | — |
反応手順
1,4-Dimethyl-1H-pyrazole-3-carboxylic acid (190 mg) was weighed to a round bottom flask and thionyl chloride (1 ml) was added. The reaction was heated to reflux for 6 h then overnight at RT. After this time thionyl chloride was evaporated and the residue azeotroped with toluene to afford the title compound, 200 mg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09326987B2 |
| 出典データセット | uspto-grants-2016_05 |
| ORD ID | ord-c376dc8ae7c445a988d94f474b950868 |
| 出典メモ | uspto-grants-2016_05 |