5-Methylthiophene-2-carboxylic acid → HCID 67726023、化合物

HRID 52065

反応式

HRID 52065 の反応式
[N:1]1([CH2:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([O:14][CH2:15]/[CH:16]=[CH:17]\[CH2:18][NH2:19])[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:20][C:21]1[S:25][C:24]([C:26](O)=[O:27])=[CH:23][CH:22]=1>>[CH3:20][C:21]1[S:25][C:24]([C:26]([NH:19][CH2:18]/[CH:17]=[CH:16]\[CH2:15][O:14][C:10]2[CH:9]=[C:8]([CH2:7][N:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)[CH:13]=[CH:12][N:11]=2)=[O:27])=[CH:23][CH:22]=1

参加物

3

反応物 2

HCID 747135-Methylthiophene-2-carboxylic acidHCID 136724732-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)-

生成物 1

HCID 67726023HCID 67726023、化合物

実験手順

Following a procedure similar to that described in Example 13, but using 4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenylamine and 5-methyl-2-thiophenecarboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound, melting at 71°-73° C., was obtained in a yield.

出典と根拠

ORDレコード
ord-ae746ef437eb498d8a09028bcde7c905
出典データセット
uspto-grants-1997_04
特許番号
US05616579

関連ノート

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