Potassium Hydroxide → Potassium 5-chloro-2-fluoro-4-nitrophenolate
反応式
[Cl:1][C:2]1[CH:7]=[C:6](F)[C:5]([F:9])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[OH-:13].[K+:14]>>[Cl:1][C:2]1[C:3]([N+:10]([O-:12])=[O:11])=[CH:4][C:5]([F:9])=[C:6]([O-:13])[CH:7]=1.[K+:14]参加物
3
実験手順
A mixture of 1-chloro-4,5-difluoro-2-nitrobenzene (5.12 g, 26.5 mmol) and 15% aqueous KOH (19.9 g) solution was stirred at reflux for 3 hours, then cooled to rt, and filtered to give the title compound as a yellow crystalloid (5.67 g, 93.3%).
後処理
- temperatureat reflux for 3 hours
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-3fb35ed3732e4e43b5745b8e21655155
- 出典データセット
- uspto-grants-2016_05
- 特許番号
- US09326975B2
反応ノート
読み込み中…