化工社化工社 化学情報印刷レポート · 研究参考用
3,4-dihydro-2H-pyran → 2H-Pyran, 2-(4-chlorobutoxy)tetrahydro-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 反応物 | 4-Chloro-1-butanol | HCID 13569 | — |
| 触媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | 2H-Pyran, 2-(4-chlorobutoxy)tetrahydro- | HCID 170488 | 89.9% |
反応手順
Dihydropyran (15.5 g) was added dropwise to a mixture of 4-chlorobutanol (20 g) and hydrochloric acid (18 M, 1 drop) at RT. The mixture was stirred for 30 min and washed with H2O (100 ml), aqueous NaHCO3 (1 M, 50 ml) and BR (50 ml). The dried liquid was heated under reduced pressure to leave the title compound as a colourless liquid (31.9 g). T.l.c. [L] Rf 0.5.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05243076 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-8d888550453845d89f366f2eeaefe39f |
| 出典メモ | uspto-grants-1993_09 |