Acetamide → HCID 605997、化合物
反応式
Br[C:2]1[CH:7]=[CH:6][C:5]([Si:8]([CH3:11])([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[C:12]([NH2:15])(=[O:14])[CH3:13].C(=O)([O-])[O-].[K+].[K+].CNCCNC>[Cu]I.C1(C)C(C)=CC=CC=1>[CH3:9][Si:8]([CH3:11])([CH3:10])[C:5]1[CH:6]=[CH:7][C:2]([NH:15][C:12](=[O:14])[CH3:13])=[CH:3][CH:4]=1参加物
7
実験手順
Under a flow of argon, in a 1 L-recovery flask, 35 g of 1-bromo-4-(trimethylsilyl)benzene, 22.6 g of acetamide, 5.8 g of copper(I)iodide, 42.2 g of potassium carbonate, and 380 mL of xylene were placed. After stirring, 6.6 mL of N,N′-dimethylethylenediamine was added. The resultant was heated and stirred at reflux for 18 hours.
後処理
- temperatureThe resultant was heated
- stirringstirred
- temperatureat reflux for 18 hours
出典と根拠
- ORDレコード
- ord-f2e389c221644e33b613cad9ed947951
- 出典データセット
- uspto-grants-2016_05
- 特許番号
- US09331285B2
反応ノート
読み込み中…