1,8-Dichloroanthraquinone → 1,8-Bis{[2-(dimethylamino)ethyl]amino}anthracene-9,10-dione

HRID 522935

反応式

HRID 522935 の反応式
Cl[C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3Cl)[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:19][N:20]([CH3:24])[CH2:21][CH2:22][NH2:23]>O>[CH3:19][N:20]([CH3:24])[CH2:21][CH2:22][NH:23][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3[NH:23][CH2:22][CH2:21][N:20]([CH3:24])[CH3:19])[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 67081,8-DichloroanthraquinoneHCID 66053N,N-Dimethylethylenediamine

生成物 1

HCID 143201191,8-Bis{[2-(dimethylamino)ethyl]amino}anthracene-9,10-dione

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 1,8-dichloroanthraquinone (5.5 g, 20 mmol) and N,N-dimethylethylenediamine (40 mL) was refluxed for 18 h. The mixture was cooled to room temperature and diluted with water to precipitate the title compound which was recrystallised from methanol to afford Compound 6 (4.5 g). The structure of Compound 6 is given below:

後処理

  1. temperaturewas refluxed for 18 h
  2. customto precipitate the title compound which
  3. customwas recrystallised from methanol

出典と根拠

ORDレコード
ord-0272c4eb373b4ee89275b9904cf25ac8
出典データセット
uspto-grants-2016_05
特許番号
US09334281B2

関連ノート

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