Dithiooxamide → 2,5-Bis(3-tetradecoxycarbonyl-2-thienyl)-thiazolo[5,4-d]thiazole

HRID 523440ノート

反応式

HRID 523440 の反応式
[CH2:1]([O:15][C:16]([C:18]1[CH:22]=[CH:21][S:20][C:19]=1[CH:23]=O)=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[NH2:25][C:26]([C:28]([NH2:30])=[S:29])=[S:27]>>[CH2:1]([O:15][C:16]([C:18]1[CH:22]=[CH:21][S:20][C:19]=1[C:23]1[S:27][C:26]2[N:25]=[C:23]([C:19]3[S:20][CH:21]=[CH:22][C:18]=3[C:16]([O:15][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])=[O:17])[S:29][C:28]=2[N:30]=1)=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

参加物

3

反応物 2

HCID 2777982DithiooxamideHCID 86717684Tetradecyl-2-formylthiophene-3-carboxylate

生成物 1

HCID 672935452,5-Bis(3-tetradecoxycarbonyl-2-thienyl)-thiazolo[5,4-d]thiazole

反応条件

温度
200 °C

実験手順

To a 25 mL flask were added 0.978 g (2.8 mmol) of tetradecyl-2-formylthiophene-3-carboxylate and 110 mg (0.9 mmol) of dithiooxamide. This mixture was heated to 200° C. for 2 hours. The resulting mixture was purified by column chromatography using a mixture of hexane and dichloromethane to give the desired compound. The NMR data were obtained and were consistent with those of the desired compound.

後処理

  1. customThe resulting mixture was purified by column chromatography
  2. additiona mixture of hexane and dichloromethane

出典と根拠

ORDレコード
ord-2c570901f56a42438a3ee8151bf3eb2f
出典データセット
uspto-grants-2016_05
特許番号
US09337358B2

反応ノート

読み込み中…