Br[C:2]1[CH:21]=[CH:20][CH:19]=[CH:18][C:3]=1[CH2:4][N:5]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O.[Br-].C([N+](C)(C)C)C1C=CC=CC=1.CC(O)=O.CC(O)=O.[Pd]>[C:6]1([N:5]2[CH2:4][C:3]3[C:18](=[CH:19][CH:20]=[CH:21][CH:2]=3)[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]2=3)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=110 g (0.295 mol) of (2-bromobenzyl)diphenylamine are dissolved in 500 ml of dimethylformamide under protective atmosphere. 3.4 g (0.075 mol) of benzyltrimethylammonium bromide and 6.1 g (0.443 mol) of potassium carbonate are added to this solution. 0.99 g (0.004 mol) of Pd(OAC)2 is subsequently added under protective gas, and the mixture is stirred at 120° C. for 9 h. After this time, the reaction mixture is cooled to room temperature and extracted with dichloromethane. The combined organic phases are dried over Na2SO4 and evaporated. The residue is recrystallised from n-heptane. The yield is 6 g (80%).
読み込み中…
