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Phenylacetic Acid → (R)-N5-(Amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-N2-(phenylacetyl)-ornithinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenylacetic Acid | HCID 999 | — |
| 反応物 | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| 反応物 | (R)-N5-[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl)-ornithinamide | HCID 136381090 | — |
| 生成物 | (R)-N5-(Amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-N2-(phenylacetyl)-ornithinamide | HCID 136381102 | 61% |
反応手順
Prepared analogously to Example 5f) from (R)-N5 -[amino (nitroimino) methyl]-N-[(4-hydroxyphenyl) methyl]ornithinamide, phenylacetic acid and TBTU in a yield of 61% of theory. It was further processed without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05616620 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-48263591402d49cfbc2c7df15a519c5e |
| 出典メモ | uspto-grants-1997_04 |