化工社化工社 化学情報印刷レポート · 研究参考用
2-(2Indenyl)indole → 6-Oxo carbazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(2Indenyl)indole | HCID 10585619 | — |
| 反応物 | Ethyl (2Z)-3-cyanoprop-2-enoate | HCID 15577688 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 溶媒 | Trifluoroacetic acid | HCID 6422 | — |
| 溶媒 | Diethylaluminum chloride | HCID 7277 | — |
| 溶媒 | Ethylaluminum dichloride | HCID 11237 | — |
| 溶媒 | Tin tetrachloride | HCID 24287 | — |
| 溶媒 | Aluminum(III) Chloride | HCID 6451240 | — |
| 生成物 | 6-Oxo carbazole | HCID 18980403 | — |
反応手順
In Method B (FIG. 2), a 2-(heteroaryl)indole derivative (1-3), or 2-(aryl)indole derivative such as 2-(2-indenyl)indole 4 is reacted with ethyl cis-β-cyanoacrylate in the presence of a catalyst such as SnCl4, AlCl3, EtAlCl2, Et2AlCl or TFA in CH2Cl2, C2H4Cl2 or toluene as solvent to give the 6-oxo carbazole compounds of formula I of the invention.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05616724 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-7186f49c7b7e4d1fbb08b8b3540eddf4 |
| 出典メモ | uspto-grants-1997_04 |