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Dimethylformamide → 2-Vinyloxyethyl phthalimide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Vinyl ether | HCID 8024 | — |
| 反応物 | 2-Chloroethyl vinyl ether | HCID 8074 | — |
| 反応物 | Phthalimide potassium salt | HCID 24194345 | — |
| 触媒 | Tetrabutylammonium Bromide | HCID 74236 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Vinyloxyethyl phthalimide | HCID 21972345 | — |
反応手順
Vinyl ether monomers for incorporation of amine-containing monomers. 2-Vinyloxy Ethyl Phthalimide was prepared via reacting 2-chloroethyl vinyl ether (25 g, 0.24 mol; CAS #110-75-8) and potassium phthalimide (25 g, 0.135 mol; CAS #1074-82-4) in 100° C. N,N-Dimethylformamide (DMF, 75 ml) using tetra n-butyl ammonium bromide (0.5 g; CAS #1643-19-2) as the phase transfer catalyst. This solution was heated for 6 h and then crashed out in water and filtered. This solid was then recrystallized twice from methanol to give white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09345775B2 |
| 出典データセット | uspto-grants-2016_05 |
| ORD ID | ord-9e8e39e6734c451382a3ca6e77c6ced6 |
| 出典メモ | uspto-grants-2016_05 |