(+/-)trans-1-Benzoyl-3,4-diazidopiperidine → HCID 69853211、化合物
反応式
[C:1]([N:9]1[CH2:14][CH2:13][C@@H:12]([N:15]=[N+]=[N-])[C@H:11]([N:18]=[N+]=[N-])[CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[C:1]([N:9]1[CH2:14][CH2:13][C@@H:12]([NH2:15])[C@H:11]([NH2:18])[CH2:10]1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
A solution of the diazide (D26) (450 mg, 1.7 mmol) in ethanol (30 ml) was treated with Lindlar catalyst (5%Pd/CaCO3, 250 mg) and stirred under hydrogen (1 atm) for 24 hour. The mixture was filtered and solvent removed in vacuo to afford the title compound as oil, 350 mg (94%).
後処理
- filtrationThe mixture was filtered
- customsolvent removed in vacuo
出典と根拠
- ORDレコード
- ord-158ddaf707b140c6a3d9b9fedf5f30af
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05616750
反応ノート
読み込み中…