2-(4-(N-cyano-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dione → 2-(4-(N-cyano-S-isopropylsulfonimidoyl)benzyl)isoindoline-1,3-dione
反応式
C(N=S(C1C=CC(CN2C(=O)C3C(=CC=CC=3)C2=O)=CC=1)(C)=[O:5])#N.[C:25]([N:27]=[S:28]([C:32]1[CH:49]=[CH:48][C:35]([CH2:36][N:37]2[C:45](=[O:46])[C:44]3[C:39](=[CH:40][CH:41]=[CH:42][CH:43]=3)[C:38]2=[O:47])=[CH:34][CH:33]=1)[CH:29]([CH3:31])[CH3:30])#[N:26]>>[C:25]([N:27]=[S:28]([C:32]1[CH:49]=[CH:48][C:35]([CH2:36][N:37]2[C:45](=[O:46])[C:44]3[C:39](=[CH:40][CH:41]=[CH:42][CH:43]=3)[C:38]2=[O:47])=[CH:34][CH:33]=1)([CH:29]([CH3:31])[CH3:30])=[O:5])#[N:26]参加物
3
実験手順
The title compound is prepared in analogy to preparation 6c, substituting 2-(4-(N-cyano-S-methylsulfinimidoyl)benzyl)isoindoline-1,3-dione with 2-(4-(N-cyano-S-isopropylsulfinimidoyl)benzyl)isoindoline-1,3-dione (preparation 14a). ESI mass spectrum: [M+H]+=368; r.t. HPLC: 3.42 min (LCMS-FA-8).
後処理
- customr.t
- custom3.42 min (LCMS-FA-8)