2-(4-(N-Cyanomethyl-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dione → 4-(N-cyanomethyl-S-methylsulfonimidoyl)benzylamine

HRID 527371ノート

反応式

HRID 527371 の反応式
NCC1C=CC(S(=NC)(N(C)C)=O)=CC=1.[C:16]([CH2:18][N:19]=[S:20]([C:23]1[CH:40]=[CH:39][C:26]([CH2:27][N:28]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:25][CH:24]=1)([CH3:22])=[O:21])#[N:17]>>[C:16]([CH2:18][N:19]=[S:20]([C:23]1[CH:40]=[CH:39][C:26]([CH2:27][NH2:28])=[CH:25][CH:24]=1)([CH3:22])=[O:21])#[N:17]

参加物

3

反応物 2

HCID 867116382-(4-(N-Cyanomethyl-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dioneHCID 899788134-(Aminomethyl)-N,N,N'-trimethylbenzenesulfonimidamide

生成物 1

HCID 899787554-(N-cyanomethyl-S-methylsulfonimidoyl)benzylamine

実験手順

The title compounds is prepared in analogy to preparation 60d, using 2-(4-(N-cyano-methyl-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dione (preparation 64a) as starting material. ESI mass spectrum: [M+H]+=224; r.t. HPLC: 0.22 min (X011_S03).

後処理

  1. customr.t

出典と根拠

ORDレコード
ord-2e25dfcbea6c4041a14f522f6dc4aa06
出典データセット
uspto-grants-2016_05
特許番号
US09346794B1

反応ノート

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