関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | 6-Decyloxy-2-naphthoyl chloride | HCID 14692669 | — |
| 反応物 | 2-Amino-4-butylphenol | HCID 15036319 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-(6-Decyloxy-2-naphthoylamino)-4-butylphenol | HCID 19736320 | 86.8% |
反応手順
In a 50 ml three-neck flask, 0.40 g (2.42 m mole) of 2-amino-4-butylphenol, 0.85 g (2.74 m mole) of 6-decyloxy-2-naphthoic acid chloride and 10 ml of dioxane were placed. To the mixture, 0.81 ml of pyridine was added dropwise under stirring at ca. 75° C. of mixture temperature. After the reaction, the reaction mixture was poured into 80 ml of water to precipitate a crystal. The crystal was filtered, washed with water and recrystallized from acetone to obtain 1.00 g of 2-(6-decyloxy-2-naphthoylamino)-4-butylphenol (Yield: 86.5%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05244596 |
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| 出典データセット | uspto-grants-1993_09 |
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| ORD ID | ord-1dfcf1ca247542b98a807a6c7678748b |
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| 出典メモ | uspto-grants-1993_09 |
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