関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Bromo-2-methylpropane | HCID 6555 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4,4'-Dihydroxybenzil | HCID 458204 | — |
| 触媒 | Tetrabutylammonium Bromide | HCID 74236 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 1,2-Bis(4-isobutoxyphenyl)ethane-1,2-dione | HCID 117600438 | 212.9% |
反応手順
1,2-Bis(4-hydroxyphenyl)ethane-1,2-dione (0.77 g, 3.18 mmol) was dissolved in 20 mL of DMF. Potassium carbonate (1.3 g, 9.4 mmol), tetrabutylammonium bromide (0.5 g, 1.55 mmol) and 1-bromo-2-methylpropane (0.86 mL, 7.91 mmol) were added, then the reaction was stirred at 130° C. overnight. The mixture was extracted with ethyl acetate and the organic phase was washed with water, dried over sodium sulfate. Concentration under vacuum gave the title compound as oil (1.2 g, quantitative).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09353089B2 |
|---|
| 出典データセット | uspto-grants-2016_05 |
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| ORD ID | ord-db3d9c4942684569a92fbb51e49d6c6c |
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| 出典メモ | uspto-grants-2016_05 |
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