Ethyl diazoacetate → HCID 90419124、化合物

反応式

[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=[CH2:12])=[N:3]1.[N+](=[CH:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[N-]>C1(C)C=CC=CC=1>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]2[CH2:12][CH:15]2[C:16]([O:18][CH2:19][CH3:20])=[O:17])=[N:3]1

参加物

実験手順

A solution of compound 2 (1.1 g, 7 mmol) in toluene (5 mL) was treated with ethyl diazoacetate (1.2 g, 10 mmol) and stirred at reflux overnight under N2. The mixture was concentrated and the residue was purified by gradient elution on silica gel (PE: EA=5:1) to afford the title compound as a pale yellow oil.

後処理

temperatureat reflux overnight under N2
concentrationThe mixture was concentrated
customthe residue was purified by gradient elution on silica gel (PE: EA=5:1)

出典と根拠

ORDレコード: ord-6cd1060211504bde9583f4969f37471c
出典データセット: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09353104B2

反応ノート

読み込み中…

参加物

反応物 2

HCID 12192Ethyl diazoacetate

HCID 206447223-Ethenyl-1-methyl-1h-indazole

生成物 1

HCID 90419124HCID 90419124、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

後処理

temperatureat reflux overnight under N2
concentrationThe mixture was concentrated
customthe residue was purified by gradient elution on silica gel (PE: EA=5:1)

出典と根拠

ORDレコード: ord-6cd1060211504bde9583f4969f37471c
出典データセット: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09353104B2

反応ノート

読み込み中…