Bromotrimethylsilane → 6-Methoxy-2-naphthylthiomethanediphosphonic Acid
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([P:22]([O:27]CC)(=[O:26])[O:23]CC)[P:14]([O:19]CC)(=[S:18])[O:15]CC)[CH:7]=[CH:6]2.C[Si](Br)(C)C>C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([P:22]([OH:26])(=[O:23])[OH:27])[P:14]([OH:19])(=[S:18])[OH:15])[CH:7]=[CH:6]2参加物
4
実験手順
Following the same method described as in Example 2, 7.15 g (15 mmol) of tetraethyl 6-methoxy-2-naphthylthiomethanediphosphonate obtained in Example 3 in dry methylene chloride was treated with trimethylsilyl bromide, and then hydrolyzed to obtain 4.21 g of the title compound as white crystals. The yield was 77%.
出典と根拠
- ORDレコード
- ord-25ec6e787a3f4a23aa117cf2e6b6a982
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05618804
反応ノート
読み込み中…