S-(o-Nitrophenyl)-N-acetyl-D-cysteine → S-(o-Nitrophenyl)-D-cysteine
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][CH2:11][C@H:12]([C:17]([OH:19])=[O:18])[NH:13]C(=O)C)([O-:3])=[O:2]>S(=O)(=O)(O)O>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10][CH2:11][C@H:12]([C:17]([OH:19])=[O:18])[NH2:13])([O-:3])=[O:2]参加物
3
反応条件
- 温度
- 0 °C
実験手順
A solution of 13.6 g (47.9 mmol) of S-(o-nitrophenyl)-N-acetyl-D-cysteine was refluxed in 57 mL of 18M sulfuric acid (H2SO4) for 1 hour. The bright yellow solution was cooled to 0° C. and concentrated. Ammonium hydroxide (NH4OH) was added to adjust the pH=5.4. The resulting precipitate was filtered and dried to yield 11.6 g (100% ) of product.
後処理
- concentrationconcentrated
- additionAmmonium hydroxide (NH4OH) was added
- filtrationThe resulting precipitate was filtered
- customdried
出典と根拠
- ORDレコード
- ord-b7167f9134904423ae762dc2aecb6d72
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05618808
反応ノート
読み込み中…