Dicyclopentylamine → [5-(3,3-Dicyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid

HRID 531910

反応式

HRID 531910 の反応式
C([O:3][C:4](=[O:26])[CH2:5][S:6][C:7]1[S:8][C:9]([NH:12][C:13]([N:15]([CH:21]2[CH2:25][CH2:24][CH2:23][CH2:22]2)[CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:14])=[N:10][N:11]=1)C.C1(NC2CCCC2)CCCC1.C(OC(=O)CSC1SC(N)=NN=1)C>>[CH:21]1([N:15]([CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)[C:13](=[O:14])[NH:12][C:9]2[S:8][C:7]([S:6][CH2:5][C:4]([OH:26])=[O:3])=[N:11][N:10]=2)[CH2:22][CH2:23][CH2:24][CH2:25]1

参加物

4

反応物 3

HCID 247671DicyclopentylamineHCID 351912Ethyl 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetateHCID 66871985[5-(3,3-Dicyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid ethyl ester

生成物 1

HCID 11394614[5-(3,3-Dicyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid

実験手順

[5-(3,3-Dicyclopentyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid ethyl ester prepared as described in general procedures (A) and (B) using dicyclopentylamine and ethyl-2-[5-amino-1,3,4-thiadiazol-2-yl-thio]acetate. Hydrolysis using general procedure (F) gave the title compound.

後処理

  1. customHydrolysis

出典と根拠

ORDレコード
ord-d9f5baff498d47f194f838335efbd75a
出典データセット
uspto-grants-2014_10
特許番号
USRE045183E1

関連ノート

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